Faculty Directory

Clyne, Alisa Morss

Clyne, Alisa Morss

Interim Department Chair
Professor
Fischell Fellow
Fischell Department of Bioengineering
Brain and Behavior Institute
Robert E. Fischell Institute for Biomedical Devices
4224 A. James Clark Hall

Ph.D., Medical and Mechanical Engineering, Harvard-MIT Division of Health Sciences and Technology
M.S., Mechanical Engineering, University of Cincinnati



B.S., Mechanical Engineering, Stanford University 
 
Dr. Clyne is director of the Vascular Kinetics Laboratory, which unravels the complexity of vascular diseases ranging from the very common (atherosclerosis, Alzheimer's disease) to the very rare (Niemann Pick). She is particularly interested in how altered blood flow (e.g., during exercise or at an arterial bifurcation) and altered blood metabolites (e.g., high glucose in diabetes) contribute to vascular disease. The laboratory uses 3D in vitro systems, computational models, and animal and human studies to discover fundamental biological mechanisms, which then enable innovative vascular disease therapies.
 
Dr. Clyne is a fellow of the American Society of Mechanical Engineering  (ASME), Biomedical Engineering Society (BMES), American Heart Association (AHA), and the American Institute for Medical and Biological Engineering (AIMBE). She received the NSF CAREER award in 2008, an AHA National Scientist Development Grant in 2010, the BMES-CMBE Rising Star award in 2011, the Association for Women in Science Elizabeth Bingham Mentoring Award in 2017, the University of Maryland Faculty Service Award and Poole & Kent Teaching Award in 2025, a Fulbright Distinguished Scholar Award in 2025, and the ASME Van C. Mow Medal in 2026. 
 
Her research and educational innovations are funded by NIH, NSF, AHA, and the Department of Education.

ENES100: Introduction to Engineering Design

BIOE331: Biofluid Mechanics

BIOE416: Cardiovascular Engineering

Grand Challenges 2.0: Engineers Partner to Unlock Solutions

Seven of 11 collaborative projects include contributions from engineering

Cholesterol Found to Play Key Role in Protecting the Blood-Brain Barrier

Clyne Lab uncovers how cholesterol helps maintain the brain’s protective barrier.

Alisa Clyne Recognized for Teaching Excellence, Faculty Service

Alisa Clyne was recognized for two faculty awards at the 2025 Faculty and Staff Recognition Celebration.

Fischell Institute Participates in Maryland Day 2025

The institute was represented by Fischell Institute Fellow Chris Jewell’s research lab, Fischell Institute Fellow Reza Ghodssi’s MEMS Sensors and Actuators Lab (MSAL), Fischell Fellow Catherine K. Kuo’s research lab, Affiliate Fellow Gregg Duncan’s Respiratory NanoBioengineering (RnB) lab, Affiliate Fellow Elisabeth Smela’s Laboratory for MicroTechnologies, Fischell Fellow Alisa Clyne’s Vascular Kinetics Lab, Affiliate Fellow Eleonora Tubaldi’s research lab, Affiliate Fellow Yancy Diaz-Mercado’s Collaborative Controls and Robotics Lab (CCRL), and Affiliate Fellow Don Milton’s Public Health AeroBiology Laboratory (PHAB Lab).

Clyne Discusses Gene-Exercise Connection in Alzheimer’s Research on Podcast

Clyne discusses how the APOE4 gene may affect the brain’s response to exercise on a new podcast.

BIOE Announces Spring 2024 Instructional Impact Awards

Three members of BIOE receive department recognition for their impactful contributions to teaching.

Katharina Maisel Promoted to Associate Professor

BIOE faculty member Dr. Katharina Maisel will be promoted to Associate Professor on July 1.

MARC Program Now Accepting Applications

The Maximizing Access to Research Careers (MARC) Program is now accepting applications from rising sophmore engineering students.

Two BIOE Students Win Outstanding Graduate Assistant Awards

BIOE's Ann Ramirez and Callie Weber received the 2023–24 Outstanding Graduate Assistant Awards.

Maisel & Mueller Win Provost's Do Good Innovator Awards

Assistant Professors Kathrina Maisel and Jenna Mueller are selected for the Do Good Innovator Awards.

MARC Students Visit the Fischell Institute

The Maximizing Access to Research Careers (MARC) program students toured the institute’s laboratory space.

Fischell Institute Attends 2023 BMES Annual Meeting

The conference was held in Seattle, Washington

UMD Researchers to Lead NIH-funded Program Supporting Underrepresented Students

The MARC award will support an educational program for traditionally underrepresented students in STEM.

Fischell Fellow Spotlight: Alisa Clyne

Clyne's area of expertise is cardiovascular mechanobiology and metabolism.

Weber, Stewart Named Fischell Fellows

BIOE names two recipients of prestigious department award

$7.9 Million in NIH Awards Propel UMD Aging Research

New multidisciplinary collaborations take on challenges like Alzheimer’s disease prevention.

Clyne, Ma, Stroka Promoted

The three BIOE faculty are promoted to Professor, Senior Lecturer, and Associate Professor, respectively.

One Size Does Not Fit All

To advance inclusive medical therapies and diversity in fundamental science, one Maryland engineer leads by example.

BBI Awards Seed Grants to Six Interdisciplinary Projects

Funded teams feature UMD faculty from 15 academic departments and six centers and institutes

Clyne, Maisel to Join BIOE Faculty in 2019

Associate, assistant professors bring expertise in endothelial cell biology, mucosal drug delivery.